Author's response to reviews Title: Derepression of Cancer/Testis Antigens in Cancer is Associated with Distinct Patterns of DNA Hypomethylation Authors:

نویسندگان

  • Robert Kim
  • Prakash Kulkarni
  • Sridhar Hannenhalli
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Cancer/Testis antigens (CTAs) as a group of tumor antigens are the novel subjects for developing cancer vaccine and immunotherapy approaches. They aberrantly express in tumors with highest normal expression in testis, and limited or no expression in normal tissues. There are important similarities between the processes of germ-cell and cancer cell development Spermatogenesis begins at puberty w...

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تاریخ انتشار 2013